The ALSFRS-R: what it measures, why we use it, and where it fails
EnsayoArtículo original publicado en inglés··2564 palabras·13 mins·#als #clinical-trials #outcome-measures #alsfrs-r
A structured tour of the ALSFRS-R: its twelve items across four functional domains, why feasibility and sensitivity to change made it the field’s standard outcome measure for twenty-five years, and a frank account of the psychometric limitations that have accumulated against it.